Propylthiouracil

CHEMBL1518 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

170.2 g/mol

LogP

0.8

Phase

4

Used to treat an overactive thyroid gland (hyperthyroidism) by blocking the production of thyroid hormones, and is sometimes used before thyroid surgery or radioactive iodine treatment. It requires regular monitoring of blood counts and liver function due to rare but serious risks of low white blood cell counts and liver damage.

Peso Molecular

170,2300 g/mol

LogP

0,80

TPSA

73,20 Å²

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Non-Small Cell Lung Cancer Stroke Breast Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

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SMILES

CCCc1cc(=O)[nH]c(=S)[nH]1

InChI

InChI=1S/C7H10N2OS/c1-2-3-5-4-6(10)9-7(11)8-5/h4H,2-3H2,1H3,(H2,8,9,10,11)

Molecular Formula

C7H10N2OS

HBD / HBA

2 / 2

Ligações Rotacionáveis

2

Átomos Pesados

11

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

Used to treat an overactive thyroid gland (hyperthyroidism) by blocking the production of thyroid hormones, and is sometimes used before thyroid surgery or radioactive iodine treatment. It requires regular monitoring of blood counts and liver function due to rare but serious risks of low white blood cell counts and liver damage.

Yes, Propylthiouracil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1518. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 657298. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

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Propylthiouracil no PillFYI

Estrutura

Dados Rápidos

Fórmula: C7H10N2OS

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.