Enterohepatic Recirculation

Pharmacokinetics

The process where a drug excreted in bile is reabsorbed from the intestine back into portal circulation. Creates secondary plasma peaks and prolongs apparent half-life.

예시

  • Oral contraceptives (antibiotic interaction)
  • Mycophenolate
  • Diclofenac

알고 계셨나요?

The process where a drug excreted in bile is reabsorbed from the intestine back into portal circulation. Creates secondary plasma peaks and prolongs apparent half-life.