CTLA4 (Cytotoxic T-Lymphocyte Antigen 4)
CTLA4
Immune checkpoint receptor that negatively regulates T cell activation at the priming stage.
기능
CTLA-4 blockade (ipilimumab) enhances T cell activation. First checkpoint inhibitor approved for melanoma.
이 표적에 작용하는 약물
| 약물 | 작용 | 주요 |
|---|---|---|
| Pembrolizumab | Other | — |
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ADRB2 (Beta-2 Adrenergic Receptor)
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HRH2 (Histamine H2 Receptor)
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