Buflomedil

CHEMBL188921 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

307.4 g/mol

LogP

2.3

Phase

4

A vasoactive drug used to treat peripheral arterial disease and symptoms of poor circulation, such as leg pain with walking. It works by relaxing blood vessel walls and reducing blood viscosity to improve tissue blood flow. It was withdrawn from several markets due to reports of serious cardiovascular and neurological adverse effects.

Peso Molecular

307,4000 g/mol

LogP

2,30

TPSA

48,00 Å²

Regra dos 5 de Lipinski

Aprovado

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

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SMILES

COc1cc(OC)c(C(=O)CCCN2CCCC2)c(OC)c1

InChI

InChI=1S/C17H25NO4/c1-20-13-11-15(21-2)17(16(12-13)22-3)14(19)7-6-10-18-8-4-5-9-18/h11-12H,4-10H2,1-3H3

Molecular Formula

C17H25NO4

HBD / HBA

- / 5

Ligações Rotacionáveis

8

Átomos Pesados

22

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

A vasoactive drug used to treat peripheral arterial disease and symptoms of poor circulation, such as leg pain with walking. It works by relaxing blood vessel walls and reducing blood viscosity to improve tissue blood flow. It was withdrawn from several markets due to reports of serious cardiovascular and neurological adverse effects.

Yes, Buflomedil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL188921. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 2467. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

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Buflomedil no PillFYI

Estrutura

Dados Rápidos

Fórmula: C17H25NO4

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.