Choline C-11
A radiotracer consisting of radiolabeled choline used in positron emission tomography (PET) imaging to detect recurrent prostate cancer. Cancer cells take up choline at increased rates as a substrate for membrane phospholipid synthesis. This allows detection of metastatic disease, particularly when conventional imaging is negative.
Peso Molecular
103,1700 g/mol
LogP
-0,40
TPSA
20,20 Ų
Regra dos 5 de Lipinski
Aprovado
Áreas Terapêuticas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estrutura 2D
Cite this structure
Embed this structure
SMILES
C[N+](C)([11CH3])CCO.[Cl-]
InChI
InChI=1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1/i1-1;
Molecular Formula
C5H14NO+
HBD / HBA
1 / 1
Ligações Rotacionáveis
2
Átomos Pesados
7
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
A radiotracer consisting of radiolabeled choline used in positron emission tomography (PET) imaging to detect recurrent prostate cancer. Cancer cells take up choline at increased rates as a substrate for membrane phospholipid synthesis. This allows detection of metastatic disease, particularly when conventional imaging is negative.
Yes, Choline C-11 is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2095207. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 449688. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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