Pemoline

CHEMBL1177 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

176.2 g/mol

LogP

0.9

Phase

4

A central nervous system stimulant formerly used to treat attention deficit hyperactivity disorder (ADHD), withdrawn from most markets due to serious liver toxicity. It worked by increasing dopamine activity but caused hepatic failure in some patients.

Peso Molecular

176,1700 g/mol

LogP

0,90

TPSA

64,70 Å²

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Type 2 Diabetes

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

Cite this structure

Embed this structure

SMILES

NC1=NC(=O)C(c2ccccc2)O1

InChI

InChI=1S/C9H8N2O2/c10-9-11-8(12)7(13-9)6-4-2-1-3-5-6/h1-5,7H,(H2,10,11,12)

Molecular Formula

C9H8N2O2

HBD / HBA

1 / 2

Ligações Rotacionáveis

1

Átomos Pesados

13

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

A central nervous system stimulant formerly used to treat attention deficit hyperactivity disorder (ADHD), withdrawn from most markets due to serious liver toxicity. It worked by increasing dopamine activity but caused hepatic failure in some patients.

Yes, Pemoline is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1177. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4723. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

Procura informações acessíveis para o paciente?

Pemoline no PillFYI

Estrutura

Dados Rápidos

Fórmula: C9H8N2O2

Links Externos

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.