Romidepsin

CHEMBL343448 Phase 4 Aprovado Protein

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

540.7 g/mol

LogP

2.2

Phase

4

A histone deacetylase inhibitor used to treat cutaneous and peripheral T-cell lymphomas that have not responded to at least one prior therapy. It works by altering gene expression in cancer cells, causing them to stop growing and die.

Peso Molecular

540,7000 g/mol

LogP

2,20

TPSA

193,00 Å²

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Melanoma Lymphoma Breast Cancer HIV/AIDS Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

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SMILES

C/C=C1\NC(=O)[C@H]2CSSCC/C=C/[C@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)[C@H](C(C)C)NC1=O

InChI

InChI=1S/C24H36N4O6S2/c1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/h6-7,9,13-15,17,19-20H,8,10-12H2,1-5H3,(H,25,31)(H,26,32)(H,27,29)(H,28,30)/b9-7+,16-6-/t15-,17-,19-,20+/m1/s1

Molecular Formula

C24H36N4O6S2

HBD / HBA

4 / 8

Ligações Rotacionáveis

2

Átomos Pesados

36

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

A histone deacetylase inhibitor used to treat cutaneous and peripheral T-cell lymphomas that have not responded to at least one prior therapy. It works by altering gene expression in cancer cells, causing them to stop growing and die.

Yes, Romidepsin is an approved drug. It has reached clinical phase 4. It is classified as a Protein.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL343448. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5352062. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Estrutura

Dados Rápidos

Fórmula: C24H36N4O6S2
Sinônimos: 1

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.