Maximum Plasma Concentration (Cmax)
CmaxThe highest plasma drug concentration achieved after administration. Reflects the rate and extent of absorption for oral drugs. Key parameter for determining peak-related toxicity and efficacy.
Exemplos
- Higher Cmax with IV vs oral
- Food effects on Cmax
- Dose-proportional Cmax in linear PK
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The highest plasma drug concentration achieved after administration. Reflects the rate and extent of absorption for oral drugs. Key parameter for determining peak-related toxicity and efficacy.