PTGS2 (Cyclooxygenase-2)
PTGS2
Inducible cyclooxygenase isoform upregulated during inflammation and pain signaling.
Функция
Catalyzes prostaglandin H2 synthesis at sites of inflammation. Primary target of NSAIDs and selective COX-2 inhibitors (coxibs).
Препараты, действующие на данную мишень
| Препарат | Действие | Первичный |
|---|---|---|
| Celecoxib | Inhibitor | Да |
| Ibuprofen | Inhibitor | Да |
| Naproxen | Inhibitor | Да |
| Acetaminophen | Inhibitor | Да |
| Aspirin | Inhibitor | — |