Monoclonal Antibody (mAb)

A laboratory-produced antibody engineered to bind a single specific epitope on a target antigen. Monoclonal antibodies are produced using hybridoma technology or recombinant methods and are classified by origin: murine (-omab), chimeric (-ximab), humanized (-zumab), or fully human (-umab). They represent the fastest-growing drug class, with applications in oncology, autoimmunity, and infectious diseases.

ตัวอย่าง

• Rituximab — anti-CD20 (non-Hodgkin lymphoma, rheumatoid arthritis)
• Adalimumab — anti-TNF-alpha (rheumatoid arthritis, Crohn's disease)
• Pembrolizumab — anti-PD-1 (multiple cancers)