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Cenobamate

CHEMBL3989949 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
267.7 g/mol
LogP
1.5
Phase
4

An antiepileptic drug with a dual mechanism, reducing repetitive neuronal firing by blocking sodium channels and enhancing gamma-aminobutyric acid (GABA) activity through modulation of GABAA receptors. It is used as adjunctive therapy for focal-onset seizures in adults. Initiation must be gradual to minimize the risk of a serious multiorgan hypersensitivity reaction called drug reaction with eosinophilia and systemic symptoms (DRESS).

Khối lượng phân tử

267,6700 g/mol

LogP

1,50

TPSA

95,90 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Epilepsy

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
NC(=O)O[C@@H](Cn1ncnn1)c1ccccc1Cl

                

                

                
                

                    
InChI

                    
InChI=1S/C10H10ClN5O2/c11-8-4-2-1-3-7(8)9(18-10(12)17)5-16-14-6-13-15-16/h1-4,6,9H,5H2,(H2,12,17)/t9-/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C10H10ClN5O2

                    

                    
                    

                        
HBD / HBA

                        
1 / 5

                    

                    
                    

                        
Liên kết có thể quay

                        
5

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
18

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
An antiepileptic drug with a dual mechanism, reducing repetitive neuronal firing by blocking sodium channels and enhancing gamma-aminobutyric acid (GABA) activity through modulation of GABAA receptors. It is used as adjunctive therapy for focal-onset seizures in adults. Initiation must be gradual to minimize the risk of a serious multiorgan hypersensitivity reaction called drug reaction with eosinophilia and systemic symptoms (DRESS).

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Cenobamate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL3989949.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 11962412.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.