Diethylcarbamazine
An antiparasitic medication used to treat lymphatic filariasis (elephantiasis), loiasis, and tropical pulmonary eosinophilia caused by filarial worms. It works by killing the microfilariae stage of the parasites and immobilizing adult worms, making them susceptible to the immune system. Severe reactions can occur when large numbers of parasites are killed rapidly.
Khối lượng phân tử
199,2900 g/mol
LogP
0,30
TPSA
26,80 Ų
Lipinski RO5
Đạt
Cơ chế tác dụng
Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.
Cấu trúc 2D
Cite this structure
Embed this structure
SMILES
CCN(CC)C(=O)N1CCN(C)CC1
InChI
InChI=1S/C10H21N3O/c1-4-12(5-2)10(14)13-8-6-11(3)7-9-13/h4-9H2,1-3H3
Molecular Formula
C10H21N3O
HBD / HBA
- / 2
Liên kết có thể quay
2
Nguyên tử nặng
14
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Câu hỏi thường gặp
An antiparasitic medication used to treat lymphatic filariasis (elephantiasis), loiasis, and tropical pulmonary eosinophilia caused by filarial worms. It works by killing the microfilariae stage of the parasites and immobilizing adult worms, making them susceptible to the immune system. Severe reactions can occur when large numbers of parasites are killed rapidly.
Disrupts essential metabolic pathways or structural components of parasitic organisms, leading to paralysis, starvation, or death of the parasite.
Yes, Diethylcarbamazine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL684. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3052. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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