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Prazosin

CHEMBL2 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
383.4 g/mol
LogP
2.0
Phase
4

Used to treat high blood pressure by relaxing and widening blood vessels, making it easier for the heart to pump blood, and is also used off-label to reduce nightmares and sleep disturbances associated with post-traumatic stress disorder. It can cause dizziness when standing up, especially with the first dose.

Khối lượng phân tử

383,4000 g/mol

LogP

2,00

TPSA

107,00 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Benign Prostatic Hyperplasia Cardiovascular Disease Respiratory Disease Pain Management Chronic Obstructive Pulmonary Disease Alzheimer's Disease Parkinson's Disease Migraine Generalized Anxiety Disorder Insomnia Infectious Disease Gastroesophageal Reflux Disease Inflammatory Bowel Disease Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Stroke Hypertension Chronic Pain Hepatitis C Heart Failure

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
COc1cc2nc(N3CCN(C(=O)c4ccco4)CC3)nc(N)c2cc1OC

                

                

                
                

                    
InChI

                    
InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)

                

                

                

                    
                    

                        
Molecular Formula

                        
C19H21N5O4

                    

                    
                    

                        
HBD / HBA

                        
1 / 8

                    

                    
                    

                        
Liên kết có thể quay

                        
4

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
28

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
Used to treat high blood pressure by relaxing and widening blood vessels, making it easier for the heart to pump blood, and is also used off-label to reduce nightmares and sleep disturbances associated with post-traumatic stress disorder. It can cause dizziness when standing up, especially with the first dose.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Prazosin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL2.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4893.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.