💊 Thuốc A-Z 🧬 Đích tác dụng 🛠 Công cụ 📚 Hướng dẫn
Tất cả thuốc Phân loại thuốc Lĩnh vực điều trị Tác dụng phụ
Hướng dẫn Từ điển thuật ngữ Dòng thời gian
So sánh Hành trình của thuốc Các họ thuốc
🇺🇸 English 🇰🇷 한국어 🇯🇵 日本語 🇨🇳 中文简体 🇪🇸 Español 🇧🇷 Português 🇮🇳 हिन्दी 🇸🇦 العربية 🇫🇷 Français 🇷🇺 Русский 🇩🇪 Deutsch 🇹🇷 Türkçe 🇻🇳 Tiếng Việt 🇮🇩 Bahasa Indonesia 🇹🇭 ไทย

Sodium Phenylacetate

CHEMBL1200358 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
158.1 g/mol
LogP
—
Phase
4

Sodium phenylacetate is a nitrogen-scavenging agent used in combination with sodium benzoate for the emergency treatment of acute hyperammonemia in patients with urea cycle disorders. Phenylacetate conjugates with glutamine (via phenylacetylglutamine) in the liver and kidney, enabling renal excretion of excess nitrogen that cannot be eliminated via the defective urea cycle. The combination product (Ammonul) is administered intravenously for acute hyperammonemic crisis.

Khối lượng phân tử

158,1300 g/mol

TPSA

40,10 Ų

Lĩnh vực điều trị

Bladder Cancer Pain Management Rheumatoid Arthritis Migraine Generalized Anxiety Disorder Breast Cancer Gout Chronic Pain

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
O=C([O-])Cc1ccccc1.[Na+]

                

                

                
                

                    
InChI

                    
InChI=1S/C8H8O2.Na/c9-8(10)6-7-4-2-1-3-5-7;/h1-5H,6H2,(H,9,10);/q;+1/p-1

                

                

                

                    
                    

                        
Molecular Formula

                        
C8H7NaO2

                    

                    
                    

                        
HBD / HBA

                        
- / 2

                    

                    
                    

                        
Liên kết có thể quay

                        
2

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
11

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
Sodium phenylacetate is a nitrogen-scavenging agent used in combination with sodium benzoate for the emergency treatment of acute hyperammonemia in patients with urea cycle disorders. Phenylacetate conjugates with glutamine (via phenylacetylglutamine) in the liver and kidney, enabling renal excretion of excess nitrogen that cannot be eliminated via the defective urea cycle. The combination product (Ammonul) is administered intravenously for acute hyperammonemic crisis.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Sodium Phenylacetate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200358.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 23690424.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.