DRD2 (Dopamine D2 Receptor)
DRD2
G-protein coupled receptor (Gi/o) mediating dopaminergic neurotransmission.
Chức năng
Key target for antipsychotic drugs (antagonists) and anti-parkinsonian agents (agonists). D2 blockade in the mesolimbic pathway reduces positive psychotic symptoms.
Thuốc tác dụng trên đích này
| Thuốc | Tác dụng | Chính |
|---|---|---|
| Levodopa | Agonist | Có |
| Quetiapine | Antagonist | Có |
| Aripiprazole | Partial Agonist | Có |
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HRH2 (Histamine H2 Receptor)
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