OPRM1 (Mu-Opioid Receptor)
OPRM1
G-protein coupled receptor (Gi/o) mediating analgesia, euphoria, respiratory depression, and physical dependence.
Chức năng
Primary target for opioid analgesics (morphine, fentanyl, oxycodone). Activation produces potent analgesia but also respiratory depression and addiction.
Thuốc tác dụng trên đích này
Related Targets
ADRB1 (Beta-1 Adrenergic Receptor)
ADRB1
ADRB2 (Beta-2 Adrenergic Receptor)
ADRB2
AGTR1 (Angiotensin II Type 1 Receptor)
AGTR1
DRD2 (Dopamine D2 Receptor)
DRD2
SIGMAR1 (Sigma-1 Receptor)
SIGMAR1
PDCD1 (Programmed Cell Death Protein 1)
PDCD1
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4)
CTLA4
HRH2 (Histamine H2 Receptor)
HRH2