OPRM1 (Mu-Opioid Receptor)
OPRM1
G-protein coupled receptor (Gi/o) mediating analgesia, euphoria, respiratory depression, and physical dependence.
Função
Primary target for opioid analgesics (morphine, fentanyl, oxycodone). Activation produces potent analgesia but also respiratory depression and addiction.
Medicamentos que Atuam neste Alvo
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PDCD1 (Programmed Cell Death Protein 1)
PDCD1
SIGMAR1 (Sigma-1 Receptor)
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AGTR1 (Angiotensin II Type 1 Receptor)
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CTLA4 (Cytotoxic T-Lymphocyte Antigen 4)
CTLA4
ADRB1 (Beta-1 Adrenergic Receptor)
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ADRB2 (Beta-2 Adrenergic Receptor)
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DRD2 (Dopamine D2 Receptor)
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HRH2 (Histamine H2 Receptor)
HRH2