OPRM1 (Mu-Opioid Receptor)
OPRM1
G-protein coupled receptor (Gi/o) mediating analgesia, euphoria, respiratory depression, and physical dependence.
İşlev
Primary target for opioid analgesics (morphine, fentanyl, oxycodone). Activation produces potent analgesia but also respiratory depression and addiction.
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Related Targets
PDCD1 (Programmed Cell Death Protein 1)
PDCD1
SIGMAR1 (Sigma-1 Receptor)
SIGMAR1
AGTR1 (Angiotensin II Type 1 Receptor)
AGTR1
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4)
CTLA4
ADRB1 (Beta-1 Adrenergic Receptor)
ADRB1
ADRB2 (Beta-2 Adrenergic Receptor)
ADRB2
DRD2 (Dopamine D2 Receptor)
DRD2
HRH2 (Histamine H2 Receptor)
HRH2