OPRM1 (Mu-Opioid Receptor)
OPRM1
G-protein coupled receptor (Gi/o) mediating analgesia, euphoria, respiratory depression, and physical dependence.
Funktion
Primary target for opioid analgesics (morphine, fentanyl, oxycodone). Activation produces potent analgesia but also respiratory depression and addiction.
Arzneimittel, die auf dieses Target wirken
Related Targets
PDCD1 (Programmed Cell Death Protein 1)
PDCD1
SIGMAR1 (Sigma-1 Receptor)
SIGMAR1
AGTR1 (Angiotensin II Type 1 Receptor)
AGTR1
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4)
CTLA4
ADRB1 (Beta-1 Adrenergic Receptor)
ADRB1
ADRB2 (Beta-2 Adrenergic Receptor)
ADRB2
DRD2 (Dopamine D2 Receptor)
DRD2
HRH2 (Histamine H2 Receptor)
HRH2