SIGMAR1 (Sigma-1 Receptor)
SIGMAR1
ER-resident chaperone protein involved in neuroprotection and pain modulation.
Funktion
Emerging target for neuropathic pain, depression, and neurodegenerative diseases.
Arzneimittel, die auf dieses Target wirken
| Arzneimittel | Wirkung | Primär |
|---|---|---|
| Lithium Carbonate | Other | Ja |
| Tamoxifen | Antagonist | — |
| Diphenhydramine | Binder | — |
| Pregabalin | Binder | — |
| Donepezil | Binder | — |
Related Targets
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PDCD1 (Programmed Cell Death Protein 1)
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AGTR1 (Angiotensin II Type 1 Receptor)
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CTLA4 (Cytotoxic T-Lymphocyte Antigen 4)
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ADRB1 (Beta-1 Adrenergic Receptor)
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ADRB2 (Beta-2 Adrenergic Receptor)
ADRB2
DRD2 (Dopamine D2 Receptor)
DRD2
HRH2 (Histamine H2 Receptor)
HRH2