PDCD1 (Programmed Cell Death Protein 1)
PDCD1
Immune checkpoint receptor on T cells that suppresses anti-tumor immunity.
Funktion
PD-1 inhibitors (pembrolizumab, nivolumab) reactivate exhausted T cells against tumors.
Arzneimittel, die auf dieses Target wirken
| Arzneimittel | Wirkung | Primär |
|---|---|---|
| Pembrolizumab | Antagonist | Ja |
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