AGTR1 (Angiotensin II Type 1 Receptor)
AGTR1
G-protein coupled receptor mediating vasoconstriction and aldosterone release.
Funktion
ARBs (losartan, valsartan) selectively block AT1, providing RAAS inhibition without ACE inhibitor cough.
Arzneimittel, die auf dieses Target wirken
| Arzneimittel | Wirkung | Primär |
|---|---|---|
| Losartan | Antagonist | Ja |
| Valsartan | Antagonist | Ja |
| Amlodipine | Other | Ja |
| Spironolactone | Other | — |
Related Targets
OPRM1 (Mu-Opioid Receptor)
OPRM1
PDCD1 (Programmed Cell Death Protein 1)
PDCD1
SIGMAR1 (Sigma-1 Receptor)
SIGMAR1
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4)
CTLA4
ADRB1 (Beta-1 Adrenergic Receptor)
ADRB1
ADRB2 (Beta-2 Adrenergic Receptor)
ADRB2
DRD2 (Dopamine D2 Receptor)
DRD2
HRH2 (Histamine H2 Receptor)
HRH2