PTGS1 (Cyclooxygenase-1)
PTGS1
Constitutive cyclooxygenase isoform catalyzing prostaglandin synthesis for homeostatic functions.
الوظيفة
Converts arachidonic acid to prostaglandin H2, the precursor for thromboxane A2 (platelet aggregation) and cytoprotective prostaglandins in the gastric mucosa.
الأدوية التي تؤثر على هذا الهدف
| الدواء | الفعل | أساسي |
|---|---|---|
| Aspirin | Inhibitor | نعم |
| Acetaminophen | Inhibitor | — |
| Ibuprofen | Inhibitor | — |
| Naproxen | Inhibitor | — |