PTGS2 (Cyclooxygenase-2)
PTGS2
Inducible cyclooxygenase isoform upregulated during inflammation and pain signaling.
الوظيفة
Catalyzes prostaglandin H2 synthesis at sites of inflammation. Primary target of NSAIDs and selective COX-2 inhibitors (coxibs).
الأدوية التي تؤثر على هذا الهدف
| الدواء | الفعل | أساسي |
|---|---|---|
| Celecoxib | Inhibitor | نعم |
| Ibuprofen | Inhibitor | نعم |
| Naproxen | Inhibitor | نعم |
| Acetaminophen | Inhibitor | نعم |
| Aspirin | Inhibitor | — |