Lipinski Rule of Five Drugs

Drugs passing Lipinski's Rule of Five — predictors of good oral bioavailability.

# Drug g/mol
1 ammonia n 13 16.0300 g/mol
2 water 18.0150 g/mol
3 nitrogen 28.0140 g/mol
4 nitric oxide 30.0060 g/mol
5 oxygen 31.9990 g/mol
6 sulfur 32.0700 g/mol
7 hydrogen peroxide 34.0150 g/mol
8 alcohol 46.0700 g/mol
9 nitrous acid 47.0140 g/mol
10 guanidine 59.0700 g/mol
11 acetic acid 60.0500 g/mol
12 urea 60.0560 g/mol
13 isopropyl alcohol 60.1000 g/mol
14 urea c 13 61.0480 g/mol
15 urea c 14 62.0480 g/mol
16 vinyl chloride 62.5000 g/mol
17 propiolactone 72.0600 g/mol
18 glycine 75.0700 g/mol
19 acetohydroxamic acid 75.0700 g/mol
20 hydroxyurea 76.0550 g/mol
21 cysteamine 77.1500 g/mol
22 dimethyl sulfoxide 78.1400 g/mol
23 fomepizole 82.1000 g/mol
24 piperazine 86.1400 g/mol
25 urethane 89.0900 g/mol
26 lactic acid 90.0800 g/mol
27 glycerin 92.0900 g/mol
28 phenol 94.1100 g/mol
29 dalfampridine 94.1100 g/mol
30 phosphoric acid 97.9950 g/mol
31 cycloserine 102.0900 g/mol
32 choline c-11 103.1700 g/mol
33 oxybate 104.1000 g/mol
34 benzyl alcohol 108.1400 g/mol
35 amifampridine 109.1300 g/mol
36 hydroquinone 110.1100 g/mol
37 betazole 111.1500 g/mol
38 histamine 111.1500 g/mol
39 thiosulfuric acid 114.1500 g/mol
40 methimazole 114.1700 g/mol
41 betaine 117.1500 g/mol
42 chloroform 119.3700 g/mol
43 tromethamine 121.1400 g/mol
44 cysteine 121.1600 g/mol
45 niacinamide 122.1200 g/mol
46 niacin 123.1100 g/mol
47 pyrazinamide 123.1100 g/mol
48 mequinol 124.1400 g/mol
49 dimercaprol 124.2300 g/mol
50 foscarnet 126.0100 g/mol

Frequently Asked Questions

What does lipinski rule of five drugs mean?
Drugs passing Lipinski's Rule of Five — predictors of good oral bioavailability.
How is this ranking calculated?
This ranking is generated from our drug database, sorted by g/mol. Only approved and verified entries are included.
How many drugs are in this ranking?
This ranking includes 50 entries from the DrugFYI database.

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This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.