Loading Dose
An initial higher dose given to rapidly achieve therapeutic plasma concentrations before steady state. Calculated as Vd * target concentration / bioavailability.
예시
- Digoxin 0.5-1mg loading
- Amiodarone IV loading
- Phenytoin 15-20mg/kg loading
알고 계셨나요?
An initial higher dose given to rapidly achieve therapeutic plasma concentrations before steady state. Calculated as Vd * target concentration / bioavailability.