Carmustine

CHEMBL513 Phase 4 Aprovado Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

214.0 g/mol

LogP

1.5

Phase

4

An alkylating chemotherapy agent belonging to the nitrosourea class that works by crosslinking DNA and disrupting RNA synthesis, killing rapidly dividing cancer cells. It is used to treat brain tumors, multiple myeloma, Hodgkin's and non-Hodgkin's lymphomas. Significant bone marrow suppression and pulmonary toxicity are important concerns during therapy.

Peso Molecular

214,0500 g/mol

LogP

1,50

TPSA

61,80 Å²

Regra dos 5 de Lipinski

Aprovado

Áreas Terapêuticas

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Melanoma Multiple Sclerosis Lymphoma Breast Cancer HIV/AIDS Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Estrutura 2D

SVG PNG

Cite this structure

Embed this structure

SMILES

O=NN(CCCl)C(=O)NCCCl

InChI

InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)

Molecular Formula

C5H9Cl2N3O2

HBD / HBA

1 / 3

Ligações Rotacionáveis

4

Átomos Pesados

12

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Perguntas frequentes

An alkylating chemotherapy agent belonging to the nitrosourea class that works by crosslinking DNA and disrupting RNA synthesis, killing rapidly dividing cancer cells. It is used to treat brain tumors, multiple myeloma, Hodgkin's and non-Hodgkin's lymphomas. Significant bone marrow suppression and pulmonary toxicity are important concerns during therapy.

Yes, Carmustine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL513. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 2578. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

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Carmustine no PillFYI

Estrutura

Dados Rápidos

Fórmula: C5H9Cl2N3O2
Sinônimos: 1

Links Externos

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Aviso Médico

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.