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Carmustine

CHEMBL513 Phase 4 Đã phê duyệt Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
214.0 g/mol
LogP
1.5
Phase
4

An alkylating chemotherapy agent belonging to the nitrosourea class that works by crosslinking DNA and disrupting RNA synthesis, killing rapidly dividing cancer cells. It is used to treat brain tumors, multiple myeloma, Hodgkin's and non-Hodgkin's lymphomas. Significant bone marrow suppression and pulmonary toxicity are important concerns during therapy.

Khối lượng phân tử

214,0500 g/mol

LogP

1,50

TPSA

61,80 Ų

Lipinski RO5

Đạt

Lĩnh vực điều trị

Ovarian Cancer Pancreatic Cancer Bladder Cancer Thyroid Cancer Non-Small Cell Lung Cancer Melanoma Multiple Sclerosis Lymphoma Breast Cancer HIV/AIDS Prostate Cancer Colorectal Cancer Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Cấu trúc 2D

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
O=NN(CCCl)C(=O)NCCCl

                

                

                
                

                    
InChI

                    
InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)

                

                

                

                    
                    

                        
Molecular Formula

                        
C5H9Cl2N3O2

                    

                    
                    

                        
HBD / HBA

                        
1 / 3

                    

                    
                    

                        
Liên kết có thể quay

                        
4

                    

                    
                    
                    

                        
Nguyên tử nặng

                        
12

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Câu hỏi thường gặp

                

                    
                    

                        
                        

                            
An alkylating chemotherapy agent belonging to the nitrosourea class that works by crosslinking DNA and disrupting RNA synthesis, killing rapidly dividing cancer cells. It is used to treat brain tumors, multiple myeloma, Hodgkin's and non-Hodgkin's lymphomas. Significant bone marrow suppression and pulmonary toxicity are important concerns during therapy.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Carmustine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL513.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 2578.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Tuyên bố miễn trách y tế

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.