PTGS1 (Cyclooxygenase-1)
PTGS1
Constitutive cyclooxygenase isoform catalyzing prostaglandin synthesis for homeostatic functions.
İşlev
Converts arachidonic acid to prostaglandin H2, the precursor for thromboxane A2 (platelet aggregation) and cytoprotective prostaglandins in the gastric mucosa.
Bu Hedefe Etki Eden İlaçlar
| İlaç | Etki | Birincil |
|---|---|---|
| Aspirin | Inhibitor | Evet |
| Acetaminophen | Inhibitor | — |
| Ibuprofen | Inhibitor | — |
| Naproxen | Inhibitor | — |