Trospium Chloride

CHEMBL3084748 Phase 4 已批准 Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

428.0 g/mol

LogP

—

Phase

4

Trospium chloride is the chloride salt form of trospium, a quaternary ammonium antimuscarinic used for overactive bladder syndrome by selectively blocking M3 muscarinic receptors in bladder smooth muscle. It reduces detrusor overactivity, decreasing urinary urgency, frequency, and incontinence episodes. The quaternary ammonium structure minimizes blood-brain barrier penetration, offering a favorable CNS safety profile.

分子量

428.0000 g/mol

TPSA

46.50 Å²

治疗领域

Chronic Obstructive Pulmonary Disease Alzheimer's Disease Schizophrenia Bipolar Disorder Obesity

Pharmacokinetics (PK)

Pharmacodynamics (PD)

二维结构

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SMILES

O=C(O[C@H]1C[C@H]2CC[C@@H](C1)[N+]21CCCC1)C(O)(c1ccccc1)c1ccccc1.[Cl-]

InChI

InChI=1S/C25H30NO3.ClH/c27-24(25(28,19-9-3-1-4-10-19)20-11-5-2-6-12-20)29-23-17-21-13-14-22(18-23)26(21)15-7-8-16-26;/h1-6,9-12,21-23,28H,7-8,13-18H2;1H/q+1;/p-1/t21-,22+,23+;

Molecular Formula

C25H30ClNO3

HBD / HBA

1 / 4

可旋转键数

5

重原子数

30

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

常见问题

Trospium chloride is the chloride salt form of trospium, a quaternary ammonium antimuscarinic used for overactive bladder syndrome by selectively blocking M3 muscarinic receptors in bladder smooth muscle. It reduces detrusor overactivity, decreasing urinary urgency, frequency, and incontinence episodes. The quaternary ammonium structure minimizes blood-brain barrier penetration, offering a favorable CNS safety profile.

Yes, Trospium Chloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3084748. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5284631. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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结构

快速数据

分子式: C25H30ClNO3
同义词: 2

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医疗免责声明

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.