SLC6A4 (Serotonin Transporter)
SLC6A4
Sodium-dependent serotonin transporter responsible for reuptake of 5-HT from the synaptic cleft.
기능
Primary target for SSRIs and SNRIs. Inhibition increases synaptic serotonin.
이 표적에 작용하는 약물
| 약물 | 작용 | 주요 |
|---|---|---|
| Duloxetine | Inhibitor | 예 |
| Escitalopram | Inhibitor | 예 |
| Fluoxetine | Inhibitor | 예 |
| Sertraline | Inhibitor | 예 |
| Venlafaxine | Inhibitor | 예 |
| Trazodone | Inhibitor | — |
| Tramadol | Inhibitor | — |