SLC6A4 (Serotonin Transporter)
SLC6A4
Sodium-dependent serotonin transporter responsible for reuptake of 5-HT from the synaptic cleft.
Função
Primary target for SSRIs and SNRIs. Inhibition increases synaptic serotonin.
Medicamentos que Atuam neste Alvo
| Medicamento | Ação | Primário |
|---|---|---|
| Duloxetine | Inhibitor | Sim |
| Escitalopram | Inhibitor | Sim |
| Fluoxetine | Inhibitor | Sim |
| Sertraline | Inhibitor | Sim |
| Venlafaxine | Inhibitor | Sim |
| Trazodone | Inhibitor | — |
| Tramadol | Inhibitor | — |