SCN9A (Sodium Channel Nav1.7)

SCN9A

Voltage-gated sodium channel preferentially expressed in nociceptive neurons.

功能

Gain-of-function mutations cause inherited pain disorders. Blocking reduces pain signaling.

作用于该靶点的药物

药物 作用 主要
Valproic Acid Blocker
Topiramate Blocker
Phenytoin Blocker
Gabapentin Blocker
Pregabalin Blocker
Lamotrigine Blocker
Carbamazepine Blocker
Furosemide Inhibitor
Hydrochlorothiazide Inhibitor

Related Targets