PTGS2 (Cyclooxygenase-2)
PTGS2
Inducible cyclooxygenase isoform upregulated during inflammation and pain signaling.
기능
Catalyzes prostaglandin H2 synthesis at sites of inflammation. Primary target of NSAIDs and selective COX-2 inhibitors (coxibs).
이 표적에 작용하는 약물
| 약물 | 작용 | 주요 |
|---|---|---|
| Celecoxib | Inhibitor | 예 |
| Ibuprofen | Inhibitor | 예 |
| Naproxen | Inhibitor | 예 |
| Acetaminophen | Inhibitor | 예 |
| Aspirin | Inhibitor | — |