PTGS2 (Cyclooxygenase-2)
PTGS2
Inducible cyclooxygenase isoform upregulated during inflammation and pain signaling.
Fonction
Catalyzes prostaglandin H2 synthesis at sites of inflammation. Primary target of NSAIDs and selective COX-2 inhibitors (coxibs).
Médicaments agissant sur cette cible
| Médicament | Action | Principal |
|---|---|---|
| Celecoxib | Inhibitor | Oui |
| Ibuprofen | Inhibitor | Oui |
| Naproxen | Inhibitor | Oui |
| Acetaminophen | Inhibitor | Oui |
| Aspirin | Inhibitor | — |