PTGS2 (Cyclooxygenase-2)
PTGS2
Inducible cyclooxygenase isoform upregulated during inflammation and pain signaling.
Função
Catalyzes prostaglandin H2 synthesis at sites of inflammation. Primary target of NSAIDs and selective COX-2 inhibitors (coxibs).
Medicamentos que Atuam neste Alvo
| Medicamento | Ação | Primário |
|---|---|---|
| Celecoxib | Inhibitor | Sim |
| Ibuprofen | Inhibitor | Sim |
| Naproxen | Inhibitor | Sim |
| Acetaminophen | Inhibitor | Sim |
| Aspirin | Inhibitor | — |